China (Mainland)
Ticarcillin disodium salt 98% supplier in China CAS NO.4697-14-7
- Min.Order: 0 Metric Ton
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- Product Details
Keywords
- Ticarcillin disodium salt supplier
- Ticarcillin disodium salt China
- Ticarcillin disodium salt 98%
Quick Details
- ProName: Ticarcillin disodium salt 98% supplier...
- CasNo: 4697-14-7
- Molecular Formula: C15H14N2Na2O6S2
- Appearance: powder
- Application: API
- PackAge: 7.5KG
- Port: shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: Desiccate at -20° C
- Transportation: ordinary goods
- LimitNum: 0 Metric Ton
Superiority
High quality product, competitive price and best service.
Details
1. Introduction of Ticarcillin disodium salt
Ticarcillin disodium salt(4697-14-7) is an antibiotic derived from penicillin similar to carbenicillin in action. It is also known as N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-3-thiophenemalonamic acid disodium salt. This chemical's molecular formula is C15H14N2Na2O6S2 and molecular weight is 428.39. What's more, its systematic name is Disodium (2S,5R,6R)-6-{[carboxylato(3-thienyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. Its classification codes are: (1)Antibacterial; (2)Drug / Therapeutic Agent; (3)Reproductive Effect.
2. Basic Information of Ticarcillin disodium salt
1). Properties of Ticarcillin disodium salt
Physical properties of Ticarcillin disodium salt are: (1)#H bond acceptors: 8; (2)#H bond donors: 3; (3)#Freely Rotating Bonds: 5; (4)Polar Surface Area: 174.42 ?2.
2). Descriptors of Structure
You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].[Na+].O=C([O-])[C@@H]2N3C(=O)[C@@H](NC(=O)C(c1ccsc1)C([O-])=O)[C@H]3SC2(C)C
(2)Std. InChI: InChI=1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7?,8-,9+,12-;;/m1../s1
(3)Std. InChIKey: ZBBCUBMBMZNEME-UBXQQCHXSA-L
3). Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | > 4gm/kg (4000mg/kg) |
GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| dog | LD50 | subcutaneous | 7gm/kg (7000mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. | |
| mouse | LD50 | intraperitoneal | 7800mg/kg (7800mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| mouse | LD50 | intravenous | 5200mg/kg (5200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| mouse | LD50 | oral | > 16gm/kg (16000mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| mouse | LD50 | subcutaneous | 10700mg/kg (10700mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. | |
| rabbit | LD50 | intravenous | > 8gm/kg (8000mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. | |
| rabbit | LD50 | subcutaneous | > 11gm/kg (11000mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH | Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| rat | LD50 | intraperitoneal | 7200mg/kg (7200mg/kg) |
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| rat | LD50 | intravenous | 5350mg/kg (5350mg/kg) |
KIDNEY, URETER, AND BLADDER: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| rat | LD50 | oral | 16gm/kg (16000mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
| rat | LD50 | subcutaneous | 10gm/kg (10000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE |
Kiso to Rinsho. Clinical Report. Vol. 12, Pg. 556, 1978. |
4) uses of Ticarcillin disodium salt
Ticarcillin disodium salt can be used for the treatment of clinical sepsis, urinary tract infections, respiratory infections and biliary tract infections, and also used in patients with leukemia and malignant secondary infection. It is also valid with typhoid fever.
5) Storage
Desiccate at -20° C
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6) Other information
When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. It may cause sensitisation by inhalation and skin contact. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing and gloves.
